Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049117 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP1A2MAPTTRPM8MC4R | |
| SCHEMBL3454027 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP1A2MAPTHPGDLMNA | |
| SCHEMBL23708646 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2MAPTTRPM8MC4R | |
| SCHEMBL3332542 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP1A2MAPTTRPM8MC4R | |
| SCHEMBL26288504 | 0.81 | MAPT (0.42) | ALDH1A1MAPTTRPM8HPGDRXFP1 | |
| SCHEMBL23703077 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CYP1A2MAPTTRPM8HPGD | |
| SCHEMBL26281760 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP1A2MAPTTRPM8HPGD | |
| SCHEMBL20439915 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP1A2MAPTTRPM8MC4R | |
| SCHEMBL3454323 | 0.76 | ALDH1A1 (0.51) | ALDH1A1CYP1A2MAPTTRPM8MC4R | |
| SCHEMBL5552417 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2MAPTTRPM8MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | CDK1, CDKN1A, CDKL1 | ALDH1A1 3077/4885CYP1A2 2661/4885MAPT 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.