Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 3/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719635 | 0.84 | NPC1 (0.49) | ALDH1A1HSD17B10CYP1A2MC4RHPGD | |
| SCHEMBL30740576 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP1A2HPGDLMNA | |
| SCHEMBL2720641 | 0.82 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CYP1A2HPGDLMNA | |
| SCHEMBL15581984 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1A2HPGDLMNA | |
| SCHEMBL2720481 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1A2MC4RHPGD | |
| SCHEMBL2717529 | 0.79 | LMNA (0.63) | ALDH1A1HSD17B10CYP1A2HPGDLMNA | |
| SCHEMBL3454027 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2HPGDLMNA | |
| SCHEMBL3332542 | 0.78 | ALDH1A1 (0.66) | ALDH1A1HSD17B10CYP1A2MC4RHPGD | |
| SCHEMBL26288487 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP1A2MC4RHPGD | |
| SCHEMBL2582135 | 0.75 | TRPM8 (0.68) | ALDH1A1HSD17B10MAPTSMN1; SMN2CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059041-A1 | NOVEL 6-ARYLAMINO PYRIDONE CARBOXAMIDE AS MEK INHIBITORS | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2012-05-10 | — | — | WO | disclosed |