SCHEMBL26289641

SCHEMBL26289641

NN1C2CCC1CC(F)(F)C2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22152107 0.83 APLNR (0.31) APLNR
SCHEMBL26205961 0.77
SCHEMBL10156397 0.72 LMNA (0.40) APLNR
SCHEMBL21216586 0.72 LMNA (0.40) APLNR
SCHEMBL13621433 0.71
SCHEMBL21653687 0.70 LMNA (0.31)
SCHEMBL10129912 0.69
SCHEMBL22038223 0.67
SCHEMBL22624232 0.67
SCHEMBL27815675 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023173017-A1 KRAS INHIBITORS FOR TREATING DISEASE BLOSSOMHILL THERAPEUTICS, INC. (US) 2023-09-14 WO disclosed
WO-2023173016-A1 KRAS INHIBITORS FOR TREATING DISEASE BLOSSOMHILL THERAPEUTICS, INC. (US) 2023-09-14 WO disclosed