Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26291539 | 0.90 | PTPN1 (0.58) | PTPN1MAOBKMT2AALDH1A1HPGD | |
| SCHEMBL26292249 | 0.87 | ALDH1A1 (0.41) | PTPN1SRD5A1SRD5A2KMT2AALDH1A1 | |
| SCHEMBL26291461 | 0.86 | RAB9A (0.40) | PTPN1MAOBKMT2AALDH1A1HPGD | |
| SCHEMBL26291464 | 0.83 | HDAC6 (0.47) | MAOBKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL26291477 | 0.83 | PTPN1 (0.47) | PTPN1MAOBALDH1A1HPGDCYP2C19 | |
| SCHEMBL23893381 | 0.81 | HIF1A (0.46) | PTPN1ARSRD5A1SRD5A2AHR | |
| SCHEMBL26291695 | 0.81 | ALDH1A1 (0.40) | PTPN1MAOBKMT2AALDH1A1HPGD | |
| SCHEMBL26292275 | 0.78 | KMT2A (0.40) | PTPN1KMT2AALDH1A1CYP3A4MEN1 | |
| SCHEMBL7947768 | 0.78 | PTPN1 (0.68) | PTPN1ARAHRKMT2AMIF | |
| SCHEMBL18583380 | 0.78 | RAB9A (0.47) | KMT2AMIFALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | PTPN1 4651/4885AR 4524/4885SRD5A1 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.