Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590436 | 0.90 | CA12 (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30568041 | 0.87 | MAOB (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20473365 | 0.87 | MAOB (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30568050 | 0.85 | PTPN1 (0.53) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL20473134 | 0.85 | PTPN1 (0.53) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL22245951 | 0.83 | SRD5A1 (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26291462 | 0.82 | RAB9A (0.42) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26291461 | 0.82 | RAB9A (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26292178 | 0.81 | RAB9A (0.42) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21735365 | 0.81 | S1PR1 (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | RAB9A 1119/4885NPC1 2727/4885ALDH1A1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.