Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395657 | 0.88 | PTPN1 (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23395599 | 0.83 | PDE4D (0.54) | PTPN1PDE4DAPP | |
| SCHEMBL23893560 | 0.82 | KDM4E (0.36) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23395722 | 0.82 | ALDH1A1 (0.36) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26291695 | 0.82 | ALDH1A1 (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26291692 | 0.82 | RAB9A (0.38) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26292124 | 0.81 | RAB9A (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23395686 | 0.80 | APP (0.35) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23395715 | 0.76 | ALDH1A1 (0.33) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25901309 | 0.75 | RAB9A (0.33) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | RAB9A 1119/4885NPC1 2727/4885ALDH1A1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.