Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576761 | 0.86 | CTSL (0.58) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL8913074 | 0.84 | CTSL (0.69) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL19174541 | 0.84 | CTSL (0.62) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL26308845 | 0.83 | CTSL (0.55) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL4462583 | 0.82 | LMNA (0.61) | CTSLCTSBCTSSCTSKLMNA | |
| SCHEMBL13256477 | 0.82 | CTSL (0.60) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL26349907 | 0.82 | CTSL (0.66) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL764273 | 0.81 | CTSL (0.64) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL3982639 | 0.81 | CTSL (0.58) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL13257317 | 0.80 | CTSL (0.60) | CTSLCTSBCTSSCTSKOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178299-A1 | PRODRUGS OF GANAXOLONE | MARINUS PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |