Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 6/20 | 0.71 |
| ▸ | HTT | P42858 | 6/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26296858 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL26290443 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL29844115 | 0.81 | LMNA (0.58) | SMN1; SMN2KDM4ELMNAHTTMAPK1 | |
| SCHEMBL4424697 | 0.80 | LMNA (0.68) | SMN1; SMN2KDM4ELMNAHTTALDH1A1 | |
| SCHEMBL26295470 | 0.80 | MEN1 (0.80) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL29844042 | 0.78 | LMNA (0.62) | SMN1; SMN2KDM4ELMNAHTTMAPK1 | |
| SCHEMBL26295759 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL4415946 | 0.78 | LMNA (0.61) | SMN1; SMN2KDM4ELMNAHTTALDH1A1 | |
| SCHEMBL25072412 | 0.77 | LMNA (0.53) | SMN1; SMN2KDM4ELMNAHTTMAPK1 | |
| SCHEMBL17599746 | 0.77 | MEN1 (0.74) | SMN1; SMN2KDM4ELMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234551-A2 | PYRIDAZINONES AS PARP7 INHIBITORS | Ribon Therapeutics Inc. (US) | 2023-08-30 | — | — | EP | disclosed |