Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23893555 | 0.89 | MTNR1A (0.45) | MTNR1AMTNR1BMCL1GRIK1GRIK2 | |
| SCHEMBL21735692 | 0.88 | MTNR1A (0.58) | MTNR1AMTNR1BGRIK1GRIK2ALDH1A1 | |
| SCHEMBL23395731 | 0.87 | MTNR1A (0.44) | MTNR1AMTNR1BMCL1GRIK1GRIK2 | |
| SCHEMBL23893484 | 0.87 | ALDH1A1 (0.43) | MTNR1AMTNR1BGRIK1GRIK2ALDH1A1 | |
| SCHEMBL26298661 | 0.87 | MTNR1A (0.43) | MTNR1AMTNR1BMCL1GRIK1GRIK2 | |
| SCHEMBL26292366 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BMCL1GRIK1GRIK2 | |
| SCHEMBL23395645 | 0.81 | MTNR1A (0.44) | MTNR1AMTNR1BMCL1GRIK1GRIK2 | |
| SCHEMBL22628833 | 0.81 | ALDH1A1 (0.57) | MTNR1AMTNR1BGRIK1GRIK2ALDH1A1 | |
| SCHEMBL21735536 | 0.81 | ALDH1A1 (0.45) | MTNR1AMTNR1BGRIK1GRIK2ALDH1A1 | |
| SCHEMBL23395730 | 0.80 | MTNR1A (0.42) | MTNR1AMTNR1BMCL1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | MTNR1A 1345/4885MTNR1B 837/4885MCL1 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.