SCHEMBL26302073

SCHEMBL26302073

CC(=O)c1ccn2c(C(C)=O)cc(-c3ccc(N(C)C)cc3)c2c1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 15/20 0.71
▸ BAZ2A Q9UIF9 15/20 0.71
▸ MAPT P10636 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ BRD9 Q9H8M2 3/20 0.39
▸ BRD4 O60885 2/20 0.39
▸ SMARCA2 P51531 1/20 0.38
▸ SMARCA4 P51532 1/20 0.38
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC6 Q9UBN7 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ BRD2 P25440 1/20 0.36
▸ BRD3 Q15059 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26304108 0.88 BAZ2B (0.62) BAZ2BBAZ2AMAPTNPC1RAB9A
SCHEMBL26302021 0.87 BAZ2B (0.54) BAZ2BBAZ2AMAPTBRD9BRD4
SCHEMBL26301287 0.84 BAZ2B (0.52) BAZ2BBAZ2AMAPTKDM4ENPC1
SCHEMBL26302150 0.83 BAZ2B (1.00) BAZ2BBAZ2AMAPTBRD9BRD4
SCHEMBL26300949 0.83 BAZ2B (0.51) BAZ2BBAZ2AMAPTKDM4ENPC1
SCHEMBL26301973 0.82 BAZ2B (0.65) BAZ2BBAZ2AMAPTKDM4EBRD9
SCHEMBL26302067 0.81 BAZ2B (0.53) BAZ2BBAZ2AKDM4ENPC1BRD9
SCHEMBL26302004 0.80 BAZ2B (0.47) BAZ2BBAZ2ABRD9BRD4SMARCA2
SCHEMBL26304348 0.77 MAPT (0.45) BAZ2BBAZ2AMAPTNPC1MAPK1
SCHEMBL26301036 0.74 FNTA (0.51) BAZ2BBAZ2AMAPTBRD9BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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