SCHEMBL26301942

SCHEMBL26301942

CC(=O)c1cc(-c2ccccc2)c2cc(C(F)(F)F)ccn12

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 16/20 0.51
▸ BAZ2A Q9UIF9 16/20 0.51
▸ MAT2A P31153 1/20 0.46
▸ BRD9 Q9H8M2 4/20 0.45
▸ BRD4 O60885 2/20 0.45
▸ BACE1 P56817 1/20 0.45
▸ SMARCA2 P51531 1/20 0.43
▸ SMARCA4 P51532 1/20 0.43
▸ BRD2 P25440 1/20 0.42
▸ BRD3 Q15059 1/20 0.42
▸ PTGDR2 Q9Y5Y4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301906 0.90 BAZ2B (0.49) BAZ2BBAZ2AMAT2ABRD9BRD4
SCHEMBL26301924 0.88 BAZ2B (0.47) BAZ2BBAZ2AMAT2ABRD9BRD4
SCHEMBL26300565 0.85 FNTA (0.47) BAZ2BBAZ2AMAT2ABACE1PTGDR2
SCHEMBL26301954 0.85 BAZ2B (0.49) BAZ2BBAZ2ABRD9BACE1SMARCA2
SCHEMBL26301973 0.85 BAZ2B (0.65) BAZ2BBAZ2AMAT2ABRD9BRD4
SCHEMBL26300545 0.84 FNTA (0.44) BAZ2BBAZ2AMAT2ABACE1
SCHEMBL26300393 0.83 BACE1 (0.45) MAT2ABACE1PTGDR2
SCHEMBL26302080 0.82 BAZ2B (0.67) BAZ2BBAZ2ABRD9BRD4BACE1
SCHEMBL26300513 0.81 BACE1 (0.45) MAT2ABACE1PTGDR2
SCHEMBL26302103 0.79 BAZ2B (0.75) BAZ2BBAZ2ABRD9BRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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