SCHEMBL26301973

SCHEMBL26301973

CC(=O)c1cc(-c2ccc(N(C)C)cc2)c2cc(C(F)(F)F)ccn12

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 13/20 0.65
▸ BAZ2A Q9UIF9 13/20 0.65
▸ BRD9 Q9H8M2 2/20 0.36
▸ BRD4 O60885 2/20 0.36
▸ PTGDR2 Q9Y5Y4 1/20 0.36
▸ SMARCA2 P51531 1/20 0.36
▸ SMARCA4 P51532 1/20 0.36
▸ BRAF P15056 1/20 0.35
▸ MAT2A P31153 1/20 0.35
▸ GAA P10253 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ BACE1 P56817 1/20 0.34
▸ BRD2 P25440 1/20 0.34
▸ BRD3 Q15059 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301906 0.89 BAZ2B (0.49) BAZ2BBAZ2ABRD9BRD4SMARCA2
SCHEMBL26300469 0.86 BAZ2B (0.48) BAZ2BBAZ2APTGDR2BRAFGAA
SCHEMBL26301924 0.86 BAZ2B (0.47) BAZ2BBAZ2ABRD9BRD4SMARCA2
SCHEMBL26300597 0.85 BAZ2B (0.53) BAZ2BBAZ2ABRAFMAT2AALDH1A1
SCHEMBL26301942 0.85 BAZ2B (0.51) BAZ2BBAZ2ABRD9BRD4PTGDR2
SCHEMBL26301954 0.83 BAZ2B (0.49) BAZ2BBAZ2ABRD9PTGDR2SMARCA2
SCHEMBL26302073 0.82 BAZ2B (0.71) BAZ2BBAZ2ABRD9BRD4SMARCA2
SCHEMBL26300859 0.82 BAZ2B (0.44) BAZ2BBAZ2APTGDR2BRAFGAA
SCHEMBL26300949 0.81 BAZ2B (0.51) BAZ2BBAZ2ABRAFGAAKDM4E
SCHEMBL26302150 0.79 BAZ2B (1.00) BAZ2BBAZ2ABRD9BRD4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
Send feedback