SCHEMBL26301954

SCHEMBL26301954

COc1ccc(-c2cc(C(C)=O)n3ccc(C(F)(F)F)cc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 8/20 0.49
▸ BAZ2A Q9UIF9 8/20 0.49
▸ SMARCA2 P51531 1/20 0.47
▸ SMARCA4 P51532 1/20 0.47
▸ BRD9 Q9H8M2 1/20 0.47
▸ PTGDR2 Q9Y5Y4 1/20 0.47
▸ TP53 P04637 2/20 0.43
▸ BACE1 P56817 1/20 0.41
▸ MAPT P10636 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ PTPN11 Q06124 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ MAOB P27338 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26300657 0.89 PTGDR2 (0.43) BAZ2BBAZ2ASMARCA2SMARCA4BRD9
SCHEMBL26301906 0.89 BAZ2B (0.49) BAZ2BBAZ2ASMARCA2SMARCA4BRD9
SCHEMBL26300717 0.88 PTGDR2 (0.46) PTGDR2BACE1MAPTPTPN11MAOB
SCHEMBL26300627 0.86 PTGDR2 (0.47) PTGDR2MAPTPTPN11MAOBKDM4E
SCHEMBL26300425 0.86 PTGDR2 (0.47) PTGDR2MAPTPTPN11MAOBKDM4E
SCHEMBL26301924 0.86 BAZ2B (0.47) BAZ2BBAZ2ASMARCA2SMARCA4BRD9
SCHEMBL26300580 0.85 PTGDR2 (0.46) BAZ2BBAZ2APTGDR2BACE1PTPN11
SCHEMBL26301942 0.85 BAZ2B (0.51) BAZ2BBAZ2ASMARCA2SMARCA4BRD9
SCHEMBL26301973 0.83 BAZ2B (0.65) BAZ2BBAZ2ASMARCA2SMARCA4BRD9
SCHEMBL26302067 0.82 BAZ2B (0.53) BAZ2BBAZ2ASMARCA2SMARCA4BRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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