SCHEMBL26302021

SCHEMBL26302021

CC(=O)c1ccc(-c2cc(C(C)=O)n3ccc(C(C)=O)cc23)cc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 16/20 0.54
▸ BAZ2A Q9UIF9 16/20 0.54
▸ BRD9 Q9H8M2 3/20 0.43
▸ BRD4 O60885 2/20 0.43
▸ HSD17B1 P14061 2/20 0.43
▸ SMARCA2 P51531 1/20 0.42
▸ SMARCA4 P51532 1/20 0.42
▸ MAPT P10636 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ BRD2 P25440 1/20 0.40
▸ BRD3 Q15059 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26302067 0.87 BAZ2B (0.53) BAZ2BBAZ2ABRD9SMARCA2SMARCA4
SCHEMBL26302073 0.87 BAZ2B (0.71) BAZ2BBAZ2ABRD9BRD4SMARCA2
SCHEMBL26302004 0.86 BAZ2B (0.47) BAZ2BBAZ2ABRD9BRD4SMARCA2
SCHEMBL26301013 0.86 FNTA (0.49) BAZ2BBAZ2ABRD9BRD4MAPT
SCHEMBL26302091 0.84 BAZ2B (0.74) BAZ2BBAZ2ABRD9BRD4HSD17B1
SCHEMBL26301924 0.83 BAZ2B (0.47) BAZ2BBAZ2ABRD9BRD4HSD17B1
SCHEMBL26300894 0.82 CYP2C8 (0.42) BAZ2BBAZ2A
SCHEMBL26300877 0.80 CYP2C8 (0.43) BAZ2BBAZ2A
SCHEMBL26304348 0.80 MAPT (0.45) BAZ2BBAZ2ABRD9HSD17B1SMARCA2
SCHEMBL26301036 0.80 FNTA (0.51) BAZ2BBAZ2ABRD9BRD4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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