SCHEMBL26306614

SCHEMBL26306614

COc1ccc(-c2noc(N3CCN(C(=O)Nc4ccccc4)CC3)n2)cc1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.65
▸ LMNA P02545 5/20 0.65
▸ HTT P42858 2/20 0.65
▸ NPC1 O15118 1/20 0.65
▸ ALDH1A1 P00352 3/20 0.64
▸ KDM4E B2RXH2 2/20 0.64
▸ GAA P10253 1/20 0.64
▸ MEN1 O00255 3/20 0.62
▸ KMT2A Q03164 3/20 0.62
▸ FAAH O00519 2/20 0.61
▸ TP53 P04637 4/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ THRB P10828 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584898 0.90 MAPT (0.64) MAPTLMNAHTTNPC1ALDH1A1
SCHEMBL30584995 0.89 MEN1 (0.64) MAPTLMNAHTTNPC1GAA
SCHEMBL25435931 0.87 MAPT (0.66) MAPTLMNAHTTNPC1ALDH1A1
SCHEMBL31546336 0.86 MAPT (0.71) MAPTLMNAHTTNPC1ALDH1A1
SCHEMBL31546443 0.85 MEN1 (0.84) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31546316 0.82 MAPT (0.76) MAPTLMNAHTTNPC1ALDH1A1
SCHEMBL30584872 0.80 MAPT (0.71) MAPTLMNAHTTNPC1ALDH1A1
SCHEMBL29165633 0.80 MAPT (0.65) MAPTLMNAHTTNPC1ALDH1A1
SCHEMBL4464886 0.80 FAAH (0.92) FAAH
SCHEMBL30584994 0.79 MAPT (0.70) MAPTLMNAHTTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885LMNA 1344/4885HTT 2290/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885LMNA 1344/4885HTT 2290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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