Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165624 | 0.81 | MAPT (0.63) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL31546316 | 0.80 | MAPT (0.76) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL26306614 | 0.80 | MAPT (0.65) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL31546324 | 0.78 | MAPT (0.69) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL30816313 | 0.78 | MAPT (0.64) | MAPTLMNAHTTNPC1HSD17B10 | |
| SCHEMBL17100655 | 0.78 | MAPT (0.66) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL31546336 | 0.78 | MAPT (0.71) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL30584872 | 0.78 | MAPT (0.71) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL30584994 | 0.77 | MAPT (0.70) | MAPTLMNAHTTNPC1TP53 | |
| SCHEMBL30584741 | 0.77 | MAPT (0.62) | MAPTLMNAHTTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117503772-A | Compound for inhibiting hepatitis B surface antigen and application thereof | 重庆医科大学国际体外诊断研究院 | 2024-02-06 | — | — | CN | disclosed |