Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534425 | 0.84 | CYP2A6 (0.33) | — | |
| SCHEMBL17681800 | 0.81 | CSNK2A1 (0.36) | TDP1L3MBTL1CSNK2A1 | |
| SCHEMBL19995552 | 0.81 | — | — | |
| SCHEMBL23878988 | 0.81 | CYP2A6 (0.34) | CNR1 | |
| SCHEMBL28015418 | 0.79 | CSNK2A1 (0.35) | CSNK2A1 | |
| SCHEMBL953384 | 0.78 | P2RX7 (0.37) | — | |
| SCHEMBL29813218 | 0.77 | — | — | |
| SCHEMBL23496639 | 0.77 | — | — | |
| SCHEMBL261259 | 0.76 | TAAR1 (0.31) | — | |
| SCHEMBL27759220 | 0.75 | PNMT (0.37) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605785-B | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA LTD GB | 2013-04-10 | — | — | CN | disclosed |
| EP-2057154-B1 | PYRIDO [2, 3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2012-11-14 | — | — | EP | disclosed |
| EP-2057154-B1 | PYRIDO [2, 3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2012-11-14 | — | — | EP | disclosed |
| US-8217055-B2 | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-10 | — | — | US | disclosed |
| US-8217055-B2 | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-10 | — | — | US | disclosed |
| US-8217055-B2 | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-10 | — | — | US | disclosed |
| CN-101490051-B | Pyrido [2, 3-b] pyrazine derivatives useful as herbicidal compounds | SYNGENTA LTD | 2012-05-23 | — | — | CN | disclosed |
| US-8133847-B2 | Pyrido[2,3-B]pyrazine derivatives useful as herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-8133847-B2 | Pyrido[2,3-B]pyrazine derivatives useful as herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-8133847-B2 | Pyrido[2,3-B]pyrazine derivatives useful as herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| EP-2102205-A1 | PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2009-09-23 | — | — | EP | disclosed |
| CN-101490051-A | Pyrido [2, 3-b] pyrazine derivatives useful as herbicidal compounds | SYNGENTA LTD (GB) | 2009-07-22 | — | — | CN | disclosed |
| EP-2057154-A1 | PYRIDO [2, 3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008071918-A1 | PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008071918-A1 | PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008009908-A1 | PYRIDO [2, 3-B] PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008009908-A1 | PYRIDO [2, 3-B] PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | PNPO, CBR3, CBR1 | TDP1 1642/4885L3MBTL1 1707/4885CSNK2A1 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.