Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25412405 | 0.89 | ALDH1A1 (0.40) | ALDH1A1CYP2C9RORCKDM4EUBE2N | |
| SCHEMBL26307939 | 0.89 | ALDH1A1 (0.40) | ALDH1A1CYP2C9KMT2AKDM4EUBE2N | |
| SCHEMBL25412408 | 0.89 | ALDH1A1 (0.40) | ALDH1A1CYP2C9RORCKDM4EUBE2N | |
| SCHEMBL25411163 | 0.85 | KCNN4 (0.42) | ALDH1A1CYP2C9KMT2AMEN1KDM4E | |
| SCHEMBL25411156 | 0.85 | KCNN4 (0.42) | ALDH1A1CYP2C9KMT2AMEN1KDM4E | |
| SCHEMBL26307937 | 0.83 | KDM4E (0.39) | ALDH1A1CYP2C9KMT2AMEN1KDM4E | |
| SCHEMBL25413830 | 0.83 | KDM4E (0.39) | ALDH1A1CYP2C9KDM4EUBE2NMMP2 | |
| SCHEMBL25413834 | 0.83 | KDM4E (0.39) | ALDH1A1CYP2C9KDM4EUBE2NMMP2 | |
| SCHEMBL25411887 | 0.81 | KDM4E (0.37) | ALDH1A1CYP2C9KDM4EUBE2NMMP2 | |
| SCHEMBL25411450 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C9KDM4EUBE2NMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | MISSISSIPPI STATE UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | MISSISSIPPI STATE UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | INMT, IDO2, WEE2 | NPC1 4241/4885ALDH1A1 3453/4885CYP2C9 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.