Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 20/20 | 0.75 |
| ▸ | GRK6 | P43250 | 2/20 | 0.58 |
| ▸ | GRK2 | P25098 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26309757 | 0.89 | GRK5 (0.73) | GRK5GRK6GRK2 | |
| SCHEMBL26308686 | 0.86 | GRK5 (0.76) | GRK5 | |
| SCHEMBL25311570 | 0.86 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25310990 | 0.86 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25310995 | 0.86 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311565 | 0.86 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311573 | 0.86 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25310993 | 0.86 | GRK5 (1.00) | GRK5 | |
| SCHEMBL30375960 | 0.85 | GRK5 (1.00) | GRK5 | |
| SCHEMBL16490729 | 0.85 | GRK5 (0.79) | GRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168246-A2 | SELECTIVE G PROTEIN-COUPLED RECEPTOR KINASE 5 INHIBITORS, COMPOSITIONS, AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2023-09-07 | — | — | WO | disclosed |