Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9888810 | 0.85 | ELANE (0.43) | ATML3MBTL1ELANENPY5RCYP1A2 | |
| SCHEMBL18052314 | 0.82 | ELANE (0.47) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL11861904 | 0.80 | ELANE (0.51) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL14996055 | 0.78 | ELANE (0.50) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL17617137 | 0.78 | ELANE (0.50) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL650639 | 0.78 | ELANE (0.50) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL25875136 | 0.77 | PKM (0.31) | CYP1A2SMN1; SMN2PKM | |
| SCHEMBL2296618 | 0.77 | ELANE (0.49) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL650209 | 0.77 | ATM (0.51) | ATML3MBTL1ELANECYP1A2KMT2A | |
| SCHEMBL2292808 | 0.76 | ELANE (0.45) | ATML3MBTL1ELANECYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725073-B2 | Compositions and methods for liquid phase oligonucleotide synthesis | HONGENE BIOTECH CORPORATION (US) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725073-B2 | Compositions and methods for liquid phase oligonucleotide synthesis | RNGTT, POLR2H, POLI | ATM 3167/4885L3MBTL1 220/4885ELANE 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.