SCHEMBL26311386

SCHEMBL26311386

[N-]=[N+]=NC1(CO)OC(n2cnc3c(N)ccnc32)C(F)C1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 3/20 0.45
▸ ADORA2A P29274 4/20 0.42
▸ ADORA2B P29275 3/20 0.42
▸ DNMT1 P26358 1/20 0.39
▸ DNMT3B Q9UBC3 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ ADORA3 P0DMS8 3/20 0.34
▸ ADORA1 P30542 2/20 0.34
▸ PDE2A O00408 1/20 0.34
▸ ADRA1A P35348 1/20 0.34
▸ PDE4D Q08499 1/20 0.34
▸ PDE3A Q14432 1/20 0.34
▸ CD99 P14209 1/20 0.33
▸ DPP4 P27487 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ SLC28A1 O00337 1/20 0.33
▸ MAP3K7 O43318 1/20 0.33
▸ SLC28A2 O43868 1/20 0.33
▸ GAPDH P04406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18947560 0.86 AHCY (0.44) AHCYADORA2AADORA2BDNMT1DNMT3B
SCHEMBL24831397 0.86 AHCY (0.55) AHCYADORA2AADORA2BALDH1A1HIF1A
SCHEMBL17927851 0.86 AHCY (0.55) AHCYADORA2AADORA2BALDH1A1HIF1A
SCHEMBL16214136 0.86 AHCY (0.55) AHCYADORA2AADORA2BALDH1A1HIF1A
SCHEMBL16367937 0.82 AHCY (0.41) AHCYADORA2AADORA2BDNMT1DNMT3B
SCHEMBL21614180 0.82 NT5E (0.52) AHCYADORA2AADORA2BDNMT1DNMT3B
SCHEMBL16214074 0.82 AHCY (0.41) AHCYADORA2AADORA2BALDH1A1HIF1A
SCHEMBL26311389 0.82 ADORA2A (0.42) AHCYADORA2AADORA2BDNMT1DNMT3B
SCHEMBL18072191 0.80 ADORA3 (0.48) ADORA3PDE3A
SCHEMBL16214090 0.80 ADORA3 (0.48) ADORA3PDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230277576-A1 A METHOD FOR PREVENTING OR TREATING A CORNAVIRUS INFECTIOUS DISEASE HENAN GENUINE BIOTECH CO., LTD. (CN) 2023-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230277576-A1 A METHOD FOR PREVENTING OR TREATING A CORNAVIRUS INFECTIOUS DISEASE ACE, ACE2, SARS1 AHCY 1014/4885ADORA2A 4232/4885ADORA2B 3951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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