Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 2/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20706697 | 1.00 | MAPT (0.61) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24171975 | 1.00 | MAPT (0.61) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15835969 | 0.98 | MAPT (0.63) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15835950 | 0.98 | MAPT (0.63) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2039941 | 0.98 | MAPT (0.63) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10478418 | 0.98 | MAPT (0.63) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20277362 | 0.96 | PLA2G2A (0.60) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL804882 | 0.96 | MAPT (0.57) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13991440 | 0.96 | PLA2G2A (0.60) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30257612 | 0.96 | PLA2G2A (0.60) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230276708-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230276708-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230276708-A1 | Polycyclic aromatic compound | ACVR1B, XDH, AHR | MAPT 4577/4885KDM4E 583/4885ALDH1A1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.