Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12718165 | 1.00 | L3MBTL1 (0.40) | L3MBTL1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL12718168 | 1.00 | L3MBTL1 (0.40) | L3MBTL1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL12717772 | 0.94 | S1PR1 (0.39) | L3MBTL1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL13839006 | 0.84 | TSHR (0.40) | L3MBTL1HTTCHRM3ALDH1A1KMT2A | |
| SCHEMBL25663994 | 0.84 | TSHR (0.40) | L3MBTL1HTTCHRM3ALDH1A1KMT2A | |
| SCHEMBL25769664 | 0.84 | TSHR (0.40) | L3MBTL1HTTCHRM3ALDH1A1KMT2A | |
| SCHEMBL12064296 | 0.81 | ALDH1A1 (0.47) | L3MBTL1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL10181568 | 0.81 | ALDH1A1 (0.47) | L3MBTL1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL12064295 | 0.81 | ALDH1A1 (0.47) | L3MBTL1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL10808055 | 0.80 | CHRM3 (0.38) | L3MBTL1HTTCHRM3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227302-A1 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |