SCHEMBL26314449

SCHEMBL26314449

Bc1ccc(BN(C)c2sc3ccccc3c2Nc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.45
KDM1A O60341 10/20 0.34
TDO2 P48775 1/20 0.34
EPAS1 Q99814 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26314443 0.84 IDO1 (0.44) IDO1KDM1ATDO2EPAS1MEN1
SCHEMBL26314445 0.73 IDO1 (0.48) IDO1KDM1ATDO2EPAS1MEN1
SCHEMBL26314441 0.64 IDO1 (0.66) IDO1KDM1ATDO2EPAS1MEN1
SCHEMBL26314448 0.64 IDO1 (0.60) IDO1KDM1ATDO2EPAS1MEN1
SCHEMBL15447095 0.63 IDO1 (1.00) IDO1KDM1ATDO2EPAS1
SCHEMBL11561685 0.62 IDO1 (0.62) IDO1KDM1ATDO2EPAS1MEN1
SCHEMBL13654810 0.59 ALDH1A1 (0.72) MEN1MAPTCASP3RAB9AKMT2A
SCHEMBL15443296 0.58 IDO1 (0.55) IDO1KDM1ATDO2MEN1MAPT
SCHEMBL23514221 0.57 IDO1 (0.62) IDO1KDM1ATDO2EPAS1MAPT
SCHEMBL29601561 0.57 KDM1A (0.70) IDO1KDM1AMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263058-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263058-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT NR2E3, LGR4, NCOA4 IDO1 2191/4885KDM1A 1796/4885TDO2 939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.