Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MYLK | Q15746 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25185237 | 0.90 | CYP11B2 (0.42) | UGCGCYP11B2CYP11B1MKNK1NPC1 | |
| SCHEMBL25820854 | 0.89 | NPC1 (0.41) | UGCGCYP11B2CYP11B1MAPK14NPC1 | |
| SCHEMBL24003825 | 0.89 | MAPK14 (0.41) | UGCGCYP11B2CYP11B1MAPK14MKNK1 | |
| SCHEMBL24003824 | 0.86 | CYP11B2 (0.42) | UGCGCYP11B2CYP11B1MKNK1MKNK2 | |
| SCHEMBL24003961 | 0.86 | CYP11B2 (0.39) | UGCGCYP11B2CYP11B1MKNK1NPC1 | |
| SCHEMBL24010141 | 0.86 | NPC1 (0.43) | UGCGCYP11B2CYP11B1MKNK1NPC1 | |
| SCHEMBL24003895 | 0.86 | CYP11B2 (0.41) | UGCGCYP11B2CYP11B1MKNK1MKNK2 | |
| SCHEMBL26328138 | 0.85 | CYP11B1 (0.35) | UGCGCYP11B2CYP11B1MAPK14MKNK1 | |
| SCHEMBL25820869 | 0.85 | CYP11B2 (0.37) | UGCGCYP11B2CYP11B1MAPK14MKNK1 | |
| SCHEMBL24003831 | 0.85 | TDO2 (0.39) | UGCGCYP11B2CYP11B1MAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | UGCG 1404/4885CYP11B2 860/4885CYP11B1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.