SCHEMBL26317003

SCHEMBL26317003

C=C(CCC=O)c1ccc(F)cc1F

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.47
CES1 P23141 3/20 0.47
SNCA P37840 1/20 0.36
ACKR3 P25106 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RAB9A P51151 2/20 0.34
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL25437128 0.98 CES2 (0.46) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL20268270 0.81 CES2 (0.53) CES2CES1ACKR3RAB9ANPC1
SCHEMBL3892255 0.81 CES2 (0.53) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL29788741 0.81 CES2 (0.53) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL25437126 0.81 CES2 (0.49) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL20628934 0.77 CES2 (0.47) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL20628901 0.77 CES2 (0.52) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL6945770 0.74 CES2 (0.52) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL30115025 0.74 CES2 (0.52) CES2CES1SNCAACKR3L3MBTL1
SCHEMBL26317015 0.73 CES2 (0.47) CES2CES1SNCAACKR3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028322-A1 PREPARATION METHOD FOR INTERMEDIATE COMPOUND ACTING AS SYNTHETIC POSACONAZOLE, AND INTERMEDIATE COMPOUND PREPARED THEREBY ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) 2026-01-29 US disclosed
EP-4495107-A1 PREPARATION METHOD FOR INTERMEDIATE COMPOUND ACTING AS SYNTHETIC POSACONAZOLE, AND INTERMEDIATE COMPOUND PREPARED THEREBY Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) 2025-01-22 EP disclosed
WO-2023173717-A1 PREPARATION METHOD FOR INTERMEDIATE COMPOUND ACTING AS SYNTHETIC POSACONAZOLE, AND INTERMEDIATE COMPOUND PREPARED THEREBY 浙江奥翔药业股份有限公司 2023-09-21 WO disclosed
CN-114591272-A Preparation method of intermediate compound for synthesizing posaconazole and intermediate compound prepared by same 浙江奥翔药业股份有限公司 2022-06-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028322-A1 PREPARATION METHOD FOR INTERMEDIATE COMPOUND ACTING AS SYNTHETIC POSACONAZOLE, AND INTERMEDIATE COMPOUND PREPARED THEREBY ERG28, CYP2F1, VKORC1 CES2 343/4885CES1 19/4885SNCA 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.