SCHEMBL26317248

SCHEMBL26317248

CCOC(=O)NCCc1cc(Cl)cc(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
GLA P06280 1/20 0.48
GPR35 Q9HC97 1/20 0.45
SLC13A3 Q8WWT9 1/20 0.44
TACR1 P25103 2/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
CNR1 P21554 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705198 0.86 GLA (0.57) KMT2AGLAHDAC3HDAC4HDAC1
SCHEMBL798802 0.81 THRB (0.60) KMT2AGLAHDAC3HDAC4HDAC1
SCHEMBL792986 0.80 KMT2A (0.65) KMT2AGLAHDAC3HDAC4HDAC1
SCHEMBL25780271 0.77 GPR35 (0.54) KMT2AGLAGPR35TACR1HDAC3
SCHEMBL25780182 0.77 GPR35 (0.57) KMT2AGPR35SLC13A3TACR1GAA
SCHEMBL8218888 0.76 SMN1; SMN2 (0.58) KMT2AGLAHDAC3HDAC4HDAC1
SCHEMBL793743 0.75 KMT2A (0.70) KMT2AGLAHDAC3HDAC4HDAC1
SCHEMBL15211305 0.74 TAAR1 (0.50) KMT2ASLC13A3TACR1CNR1TSHR
SCHEMBL793096 0.74 KMT2A (0.57) KMT2AGLAHDAC3HDAC4HDAC1
SCHEMBL798624 0.72 TSHR (0.58) KMT2AGLAHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3781553-B1 HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2023-08-23 EP disclosed