Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | USP2 | O75604 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYBB | P04839 | 1/20 | 0.57 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645152 | 0.92 | MAPK1 (0.83) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL21530399 | 0.92 | MAPK1 (0.83) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL21530456 | 0.88 | ALDH1A1 (0.70) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL21530421 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL15662302 | 0.82 | MAPT (0.80) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL29645154 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL21530783 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL21530407 | 0.81 | MAPK1 (0.78) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL29621879 | 0.79 | MAPK1 (0.61) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL21530418 | 0.79 | MAPK1 (0.61) | SMN1; SMN2GAAMAPK1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | SMN1; SMN2 36/4885GAA 3/4885MAPK1 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.