Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | USP2 | O75604 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYBB | P04839 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21530783 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL29621879 | 0.94 | MAPK1 (0.61) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL21530418 | 0.94 | MAPK1 (0.61) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL24019206 | 0.88 | ALDH1A1 (0.53) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL21530399 | 0.83 | MAPK1 (0.83) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL29645152 | 0.83 | MAPK1 (0.83) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL26317575 | 0.81 | SMN1; SMN2 (0.72) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL21530421 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL15662302 | 0.76 | MAPT (0.80) | SMN1; SMN2GAAALDH1A1USP2HTT | |
| SCHEMBL20355257 | 0.74 | NUDT1 (0.47) | SMN1; SMN2GAAALDH1A1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
| US-20220135535-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135535-A1 | HETEROARYL COMPOUNDS AND THEIR USE | GBA1, GBA2, GAA | SMN1; SMN2 36/4885GAA 3/4885ALDH1A1 1097/4885 |
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | SMN1; SMN2 36/4885GAA 3/4885ALDH1A1 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.