Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339001 | 0.89 | ROCK1 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29621702 | 0.89 | ROCK1 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29621886 | 0.89 | ROCK1 (0.42) | DHFRCYP1A2CYP2D6NPC1JAK2 | |
| SCHEMBL20340268 | 0.89 | ROCK1 (0.42) | DHFRCYP1A2CYP2D6NPC1JAK2 | |
| SCHEMBL20339039 | 0.87 | CYP1A2 (0.49) | DHFRCYP1A2CYP2D6NPC1MAPT | |
| SCHEMBL21530423 | 0.86 | RAB9A (0.54) | DHFRACHECYP1A2CYP2D6NPC1 | |
| SCHEMBL24019171 | 0.86 | AGPAT2 (0.54) | CYP1A2CYP2D6NPC1MAPTMAPK1 | |
| SCHEMBL26317481 | 0.86 | CYP1A2 (0.45) | ACHECYP1A2CYP2D6NPC1MAPT | |
| SCHEMBL29621980 | 0.86 | AGPAT2 (0.54) | CYP1A2CYP2D6NPC1MAPTMAPK1 | |
| SCHEMBL21530477 | 0.85 | CYP1A2 (0.47) | DHFRCYP1A2CYP2D6NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | DHFR 2908/4885ACHE 429/4885CYP1A2 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.