Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339039 | 0.89 | CYP1A2 (0.49) | CYP1A2CYP2D6AGPAT2MAPTLMNA | |
| SCHEMBL24019171 | 0.88 | AGPAT2 (0.54) | CYP1A2CYP2D6AGPAT2MAPTLMNA | |
| SCHEMBL29621980 | 0.88 | AGPAT2 (0.54) | CYP1A2CYP2D6AGPAT2MAPTLMNA | |
| SCHEMBL21530423 | 0.86 | RAB9A (0.54) | CYP1A2CYP2D6BCHEACHEMAPT | |
| SCHEMBL26318052 | 0.86 | DHFR (0.44) | CYP1A2CYP2D6AGPAT2ACHEMAPT | |
| SCHEMBL20340282 | 0.85 | RAB9A (0.44) | CYP1A2CYP2D6AGPAT2MAPTLMNA | |
| SCHEMBL20339002 | 0.85 | ABCG2 (0.47) | CYP1A2CYP2D6AGPAT2 | |
| SCHEMBL29621826 | 0.83 | ROCK1 (0.50) | ACHEMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL24019179 | 0.83 | ROCK1 (0.50) | ACHEMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL21530477 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2D6MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | CYP1A2 815/4885CYP2D6 892/4885AGPAT2 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.