Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340262 | 0.93 | CYP1A2 (0.40) | CYP1A2CYP2D6MAPTLMNANPSR1 | |
| SCHEMBL20340343 | 0.81 | ROCK1 (0.48) | CYP1A2CYP2D6MAPTNPSR1RAB9A | |
| SCHEMBL29621922 | 0.81 | ROCK1 (0.48) | CYP1A2CYP2D6MAPTNPSR1RAB9A | |
| SCHEMBL26318382 | 0.80 | CYP1A2 (0.34) | CYP1A2CYP2D6MAPTNPSR1RAB9A | |
| SCHEMBL20339039 | 0.78 | CYP1A2 (0.49) | CYP1A2CYP2D6MAPTLMNANPSR1 | |
| SCHEMBL24019191 | 0.77 | — | — | |
| SCHEMBL20339000 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP2D6MAPTLMNANPSR1 | |
| SCHEMBL20338988 | 0.74 | DHFR (0.39) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL20340271 | 0.73 | CYP1A2 (0.50) | CYP1A2CYP2D6MAPTLMNANPSR1 | |
| SCHEMBL18073542 | 0.73 | CALM1 (0.44) | NPSR1KDM4EUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | CYP1A2 815/4885CYP2D6 892/4885MAPT 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.