Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24817721 | 0.90 | CRBN (0.66) | CRBNMAP1LC3B | |
| SCHEMBL25123189 | 0.86 | CRBN (0.65) | CRBN | |
| SCHEMBL24592273 | 0.83 | CRBN (0.61) | CRBN | |
| SCHEMBL24920904 | 0.83 | CRBN (0.61) | CRBN | |
| SCHEMBL29439976 | 0.80 | CRBN (1.00) | CRBNMAP1LC3B | |
| SCHEMBL21760366 | 0.80 | CRBN (1.00) | CRBNMAP1LC3B | |
| SCHEMBL24046600 | 0.79 | CRBN (0.65) | CRBN | |
| SCHEMBL19022946 | 0.76 | CRBN (0.60) | CRBN | |
| SCHEMBL27339978 | 0.76 | CRBN (0.46) | CRBN | |
| SCHEMBL23138822 | 0.76 | CRBN (0.46) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | MUSK, ERBB2, NTRK1 | CRBN 330/4885MAP1LC3B 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.