SCHEMBL2631912

SCHEMBL2631912

CCCCC/C=C\C/C=C\CCCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)OC(CO)CCN(C)C

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.52
ALDH1A1 P00352 2/20 0.52
CNR2 P34972 2/20 0.52
FAAH O00519 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
S1PR1 P21453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24493635 1.00 CNR1 (0.52) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL4602550 0.89 DNM1 (0.41) CNR1ALDH1A1CNR2FAAH
SCHEMBL21235635 0.85 ALDH1A1 (0.43) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL2640807 0.85 ALDH1A1 (0.43) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL28862599 0.84 ALDH1A1 (0.56) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL19691883 0.84 CNR1 (0.41) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL19691884 0.84 CNR1 (0.41) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL7108549 0.82 CNR1 (0.62) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL17791303 0.82 ALDH1A1 (0.43) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL1934507 0.82 ALDH1A1 (0.43) CNR1ALDH1A1CNR2FAAHMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2355658-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2017-09-27 EP disclosed
US-9764036-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2017-09-19 US disclosed
US-20160213785-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2016-07-28 US disclosed
US-20120095075-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160213785-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS CETP, LCAT, NPC1L1 CNR1 1857/4885ALDH1A1 3880/4885CNR2 1808/4885
US-20120095075-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS CETP, LCAT, NPC1L1 CNR1 1866/4885ALDH1A1 3847/4885CNR2 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.