Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319630 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL26319700 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL25413905 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL25410319 | 0.80 | KDM4E (0.55) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL25413938 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL26319827 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL26319554 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EACHEHPGDSPLA2G10 | |
| SCHEMBL2693587 | 0.74 | PIM1 (0.51) | ALDH1A1KDM4EACHEHPGDSHTR2C | |
| SCHEMBL2694096 | 0.74 | PIM1 (0.46) | ALDH1A1KDM4EACHEHPGDSMAPT | |
| SCHEMBL25414384 | 0.74 | HTR2C (0.38) | ALDH1A1KDM4EACHEHPGDSPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170024-A1 | CAMK2 MODULATORS AND THEIR USE IN MEDICINE | UNIVERSITY OF COPENHAGEN (DK) | 2023-09-14 | — | — | WO | disclosed |