Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26320404 | 0.83 | ACHE (0.61) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL25415043 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL25410319 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL25414298 | 0.80 | ALDH1A1 (0.59) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL319326 | 0.80 | PIM1 (0.56) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL6786585 | 0.78 | ALDH1A1 (0.63) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL26319639 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL352152 | 0.75 | HPGDS (0.73) | KDM4EALDH1A1ACHEHPGDSPTGER1 | |
| SCHEMBL24136179 | 0.75 | ALDH1A1 (0.71) | KDM4EALDH1A1ACHEHPGDSHDAC1 | |
| SCHEMBL2693587 | 0.74 | PIM1 (0.51) | KDM4EALDH1A1ACHEHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170024-A1 | CAMK2 MODULATORS AND THEIR USE IN MEDICINE | UNIVERSITY OF COPENHAGEN (DK) | 2023-09-14 | — | — | WO | disclosed |