Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL29824737 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL6332969 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL9474227 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL8467361 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL11054858 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL4111185 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL263200 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL191753 | 1.00 | TSHR (0.67) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL7804046 | 0.97 | TSHR (0.62) | TSHRLMNACYP3A4TDP1BLM | |
| Cadaverine Tartrate SCHEMBL4953538 | 0.97 | TSHR (0.62) | TSHRLMNACYP3A4TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1745 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116407494-B | Degarelix acetate injection and preparation method and application thereof | 山东大学齐鲁医院 | 2024-07-09 | — | — | CN | claimed |
| CN-114246953-B | Anti-cMet antibody drug conjugates and methods of use thereof | 艾伯维生物制药股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118078744-A | Polymyxin E sodium mesylate injection and preparation process thereof | 南京正科医药股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117838671-A | Inhalation solution pharmaceutical composition containing vilanaterol and preparation method thereof | 四川海思科制药有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-115612114-B | Copolymer membrane and method for enzymatic self-assembly synthesis and application thereof | 中国科学院天津工业生物技术研究所 | 2024-02-20 | — | — | CN | claimed |
| CN-115612403-B | Self-assembled strong-adhesion copolymer film, coating method and application | 中国科学院天津工业生物技术研究所 | 2023-12-01 | — | — | CN | claimed |
| CN-116926100-A | Preparation method of immobilized lignin peroxidase and application of immobilized lignin peroxidase in fields of straw degradation, printing and dyeing wastewater treatment and the like | 江苏大学 | 2023-10-24 | — | — | CN | claimed |
| CN-115944642-B | Ursodeoxycholic acid sustained release preparation and preparation method thereof | 杭州沐源生物医药科技有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116407494-A | Degarelix acetate injection and preparation method and application thereof | 山东大学齐鲁医院 | 2023-07-11 | — | — | CN | claimed |
| CN-116370441-A | Budesonide suspension for inhalation and preparation method thereof | 杭州百诚医药科技股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-101596179-A | A kind of pharmaceutical composition for the treatment of hyperammonemia and preparation method thereof | FUREN MEDICINES GROUP (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101549146-A | Romurtide injection and preparation method thereof | BEIJING JIASHI LIANBO PHARMACE (CN) | 2009-10-07 | — | — | CN | claimed |
| CN-101152146-A | Hydrochloric acid olprinone injection and method for preparing the same | BEIJING DEZHONG WANQUAN MEDICINE TECHNOLOGY DEV CO LTD (CN) | 2008-04-02 | — | — | CN | claimed |
| CN-101053578-A | Gingko leaf extract injection containing ginkgolide and preparation method thereof | UNIV FUDAN (CN) | 2007-10-17 | — | — | CN | claimed |
| CN-1965818-A | Prescription for preparing high-quality tranexamic acid injection and preparation process thereof | HAINAN SAKER MEDICINE CO LTD (CN) | 2007-05-23 | — | — | CN | claimed |
| CN-1430968-A | Injection liquid of extractive gingko leaves and its preparing method | UNIV FUDAN (CN) | 2003-07-23 | — | — | CN | claimed |
| US-6355099-B1 | Plaster mixture for forming a machinable composition | UNITED STATES GYPSUM COMPANY | 2002-03-12 | — | — | US | claimed |
| EP-0433977-B1 | Method for optical measurement of bilirubin and reagent therefor | NIPPON SHOJI KK (JP) | 1995-05-31 | — | — | EP | claimed |
| US-5262304-A | Reacting with a zinc compound, bilirubin oxidase in a buffer and a coloring agent | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1993-11-16 | — | — | US | claimed |
| EP-0433977-A2 | Method for optical measurement of bilirubin and reagent therefor | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1991-06-26 | — | — | EP | claimed |