Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 4/20 | 0.41 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL4608508 | 1.00 | TSHR (0.62) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL7992777 | 1.00 | TSHR (0.62) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL27781966 | 0.97 | TSHR (0.59) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL22325479 | 0.97 | TSHR (0.59) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL27476049 | 0.97 | TSHR (0.59) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL4111185 | 0.97 | TSHR (0.67) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL263201 | 0.97 | TSHR (0.67) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL11054858 | 0.97 | TSHR (0.67) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL263200 | 0.97 | TSHR (0.67) | TSHRLMNABLMCYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL6332969 | 0.97 | TSHR (0.67) | TSHRLMNABLMCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510521-A | Combination of budesonide and 5-amino-2, 3-dihydro-1, 4-phthalazinedione | 麦翠奥制药公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118369100-A | Combination of 5-amino-2, 3-dihydro-1, 4-phthalazinedione with 6' -methoxy cinchonine-9-ol for the treatment of coronavirus infections | 麦翠奥制药公司 | 2024-07-19 | — | — | CN | disclosed |
| US-20010046532-A1 | Method for preparing a cheese product | CONAGRA, INC. | 2001-11-29 | — | — | US | disclosed |