Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | WEE1 | P30291 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24003923 | 0.88 | CYP11B2 (0.38) | CYP11B2CYP11B1PIK3CGGRM1CBLB | |
| SCHEMBL26332882 | 0.80 | PTGES (0.37) | CYP11B2CYP11B1CBLBCYP2D6MAPK14 | |
| SCHEMBL26332893 | 0.80 | MAPK1 (0.38) | CYP11B2CYP11B1GRM1CBLBPTGES | |
| SCHEMBL26328176 | 0.80 | CYP11B2 (0.37) | CYP11B2CYP11B1PIK3CGNR1H4 | |
| SCHEMBL25185237 | 0.78 | CYP11B2 (0.42) | CYP11B2CYP11B1PIK3CGGRM1CBLB | |
| SCHEMBL24003910 | 0.75 | CYP11B2 (0.48) | CYP11B2CYP11B1PIK3CGCBLBCYP2D6 | |
| SCHEMBL25820854 | 0.75 | NPC1 (0.41) | CYP11B2CYP11B1PIK3CGGRM1CYP2D6 | |
| SCHEMBL25820869 | 0.75 | CYP11B2 (0.37) | CYP11B2CYP11B1PIK3CGGRM1CBLB | |
| SCHEMBL24010141 | 0.75 | NPC1 (0.43) | CYP11B2CYP11B1PIK3CGGRM1MKNK1 | |
| SCHEMBL24003961 | 0.75 | CYP11B2 (0.39) | CYP11B2CYP11B1PIK3CGGRM1CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | CYP11B2 860/4885CYP11B1 751/4885PIK3CG 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.