Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 10/20 | 0.59 |
| ▸ | HTR2C | P28335 | 6/20 | 0.59 |
| ▸ | HTR2B | P41595 | 6/20 | 0.59 |
| ▸ | HTR1A | P08908 | 5/20 | 0.59 |
| ▸ | HTR1B | P28222 | 4/20 | 0.53 |
| ▸ | HTR1D | P28221 | 4/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HTR5A | P47898 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26307594 | 0.90 | HTR6 (0.59) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL26323272 | 0.89 | HTR6 (0.71) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25074560 | 0.88 | HTR6 (0.54) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25074597 | 0.88 | HTR2A (0.54) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25074573 | 0.88 | HTR6 (0.54) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25074574 | 0.88 | HTR6 (0.64) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL30637142 | 0.88 | HTR6 (0.64) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25074590 | 0.87 | HTR6 (0.62) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL31404488 | 0.87 | HTR6 (0.62) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25790561 | 0.87 | HTR6 (0.62) | HTR6HTR2AHTR2CHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295086-A1 | NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES | HERCULES CAPITAL, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230295086-A1 | NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES | HERCULES CAPITAL, INC. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295086-A1 | NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES | HTR2A, HTR2C, HTR5A | HTR6 8/4885HTR2A 1/4885HTR2C 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.