Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 13/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26323357 | 0.85 | ADRA2A (0.33) | PRMT5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26323330 | 0.79 | KDR (0.42) | GRIN2BNPBWR1MEN1NPC1ALDH1A1 | |
| SCHEMBL26323321 | 0.71 | KDR (0.39) | NPBWR1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL26323315 | 0.65 | CBFB (0.34) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25494178 | 0.61 | RAD52 (0.45) | PRMT5MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL11770396 | 0.61 | AURKA (0.70) | PRMT5AURKANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18415733 | 0.61 | AURKA (0.51) | AURKANPBWR1MEN1NPC1ALDH1A1 | |
| SCHEMBL5308832 | 0.60 | PRMT5 (0.53) | PRMT5GRIN2BAURKAMEN1ALDH1A1 | |
| SCHEMBL13041701 | 0.59 | TNKS (0.49) | NPBWR1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL23999971 | 0.59 | ALDH1A1 (0.55) | PRMT5MEN1NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | PRMT5 1924/4885GRIN2B 3348/4885AURKA 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.