SCHEMBL2632357

SCHEMBL2632357

Cc1cccc(Nc2nc(Nc3ccc(O)cc3)nc(Nc3cccc(C)c3)n2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 3/20 0.65
NFKB1 P19838 1/20 0.61
KCNH3 Q9ULD8 1/20 0.60
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
POLB P06746 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
HTT P42858 1/20 0.52
TP53 P04637 2/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
SLC2A1 P11166 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
NOD1 Q9Y239 1/20 0.50
GBA1 P04062 1/20 0.48
GAA P10253 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4568691 0.88 NFKB1 (0.63) AURKANFKB1KCNH3POLBNPSR1
SCHEMBL4544841 0.88 NFKB1 (0.67) AURKANFKB1KCNH3CA12CA1
SCHEMBL4544781 0.88 NFKB1 (0.67) AURKANFKB1KCNH3CA12CA1
SCHEMBL22356434 0.88 RHOA (0.54) AURKAPOLBNPSR1HTTMAPT
SCHEMBL11235317 0.88 NPSR1 (0.70) AURKANFKB1NPSR1HTTTP53
SCHEMBL30240628 0.88 NFKB1 (0.76) AURKANFKB1KCNH3CA12CA1
SCHEMBL762506 0.88 NFKB1 (0.76) AURKANFKB1KCNH3CA12CA1
SCHEMBL4544749 0.86 KCNH3 (0.77) AURKANFKB1KCNH3CA12CA1
SCHEMBL4544851 0.86 KCNH3 (0.77) AURKANFKB1KCNH3CA12CA1
SCHEMBL4544862 0.85 KCNH3 (0.70) NFKB1KCNH3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120231217-A1 OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120076956-A1 Polarizing plate, liquid crystal display device using the same and moisture- and heat-resistant protective film for polarizing plate FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-7697095-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
US-20100020273-A1 POLYMER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed
US-7611760-B2 Cellulose acylate film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-7511785-B2 Liquid crystal display having liquid crystal cell of bend alignment mode or hybrid alignment mode FUJFILM CORPORATION (JP) 2009-03-31 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed