Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATF1 | P18846 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18997062 | 0.84 | KDM4E (0.48) | ALDH1A1POLBKDM4ETSHRBCL6 | |
| SCHEMBL9170525 | 0.75 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBATF1NFKB1 | |
| SCHEMBL5562201 | 0.73 | POLB (0.51) | ALDH1A1SMN1; SMN2POLBHTTTSHR | |
| SCHEMBL9906447 | 0.72 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2POLBLMNAHTT | |
| SCHEMBL21718974 | 0.71 | CHRNB2 (0.45) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL24349000 | 0.70 | TMEM97 (0.39) | ALDH1A1SMN1; SMN2POLBLMNAHTT | |
| SCHEMBL4820737 | 0.70 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2POLBATF1NFKB1 | |
| SCHEMBL4812899 | 0.70 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2POLBATF1NFKB1 | |
| SCHEMBL9906408 | 0.70 | MEN1 (0.40) | ALDH1A1SMN1; SMN2POLBLMNAHTT | |
| SCHEMBL12874013 | 0.69 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2POLBATF1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286997-A1 | Compounds for the Treatment of Cancer and Inflammatory Disease | SHY Therapeutics LLC | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286997-A1 | Compounds for the Treatment of Cancer and Inflammatory Disease | MAPK6, MAP3K6, MAPK4 | ALDH1A1 2765/4885SMN1; SMN2 4331/4885POLB 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.