Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652339 | 0.83 | DRD2 (0.48) | CA2CA1TDP1MEN1GAA | |
| SCHEMBL5268980 | 0.83 | GAA (0.44) | CA2CA1TDP1MEN1GAA | |
| SCHEMBL10317785 | 0.83 | MEN1 (0.50) | CA2CA1MEN1GAAKMT2A | |
| SCHEMBL10317783 | 0.83 | MEN1 (0.50) | CA2CA1MEN1GAAKMT2A | |
| SCHEMBL10318441 | 0.83 | MEN1 (0.50) | CA2CA1MEN1GAAKMT2A | |
| SCHEMBL20768558 | 0.82 | MEN1 (0.47) | CA2CA1TDP1MEN1GAA | |
| SCHEMBL25495785 | 0.81 | CA2 (0.47) | CA2CA1TDP1MEN1GAA | |
| SCHEMBL19347754 | 0.81 | PTPRB (0.42) | CA2CA1MEN1GAAKMT2A | |
| SCHEMBL26324983 | 0.78 | MAPT (0.46) | CA2CA1TDP1MEN1GAA | |
| SCHEMBL19347431 | 0.78 | MAPT (0.46) | CA2CA1TDP1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234552-A2 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |