Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | THRB | P10828 | 7/20 | 0.65 |
| ▸ | BLM | P54132 | 7/20 | 0.65 |
| ▸ | RECQL | P46063 | 6/20 | 0.65 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.65 |
| ▸ | TOP2A | P11388 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.65 |
| ▸ | STAT6 | P42226 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755618 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL15607151 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL30408780 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL12000782 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL12250542 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL6668771 | 0.93 | MEN1 (0.57) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL16160572 | 0.91 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL16582272 | 0.91 | MEN1 (0.65) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL10239265 | 0.90 | MEN1 (0.69) | MEN1KMT2ATHRBBLMRECQL | |
| Daunomycinone SCHEMBL118279 | 0.89 | S100A4 (0.66) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9775914-B2 | Prodrugs activated by caspase | PHAROSGEN CO., LTD. (KR) | 2017-10-03 | — | — | US | disclosed |
| US-20160144050-A1 | PRODRUGS ACTIVATED BY CASPASE | PHAROSGEN CO., LTD. (KR) | 2016-05-26 | — | — | US | disclosed |
| US-7728040-B1 | Polyamine conjugates as selective NMDA inhibitors and anti-cancer drugs | UNIVERSITY OF CENTRAL FLORIDS RESEARCH FOUNDATION, INC. (US) | 2010-06-01 | — | — | US | disclosed |