Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793530 | 0.91 | SLC6A4 (0.46) | SLC6A4OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL17793531 | 0.91 | SLC6A4 (0.46) | SLC6A4OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL17793566 | 0.91 | SLC6A4 (0.46) | SLC6A4OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL17793529 | 0.84 | SLC6A4 (0.43) | SLC6A4OPRM1OPRK1CYP1A2CYP3A4 | |
| SCHEMBL17793538 | 0.83 | SLC6A4 (0.63) | SLC6A4OPRM1OPRK1SMN1; SMN2CYP1A2 | |
| SCHEMBL29875855 | 0.83 | SLC6A4 (0.63) | SLC6A4OPRM1OPRK1SMN1; SMN2CYP1A2 | |
| SCHEMBL29875858 | 0.83 | SLC6A4 (0.63) | SLC6A4OPRM1OPRK1SMN1; SMN2CYP1A2 | |
| SCHEMBL17793574 | 0.82 | SLC6A4 (0.37) | SLC6A4OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL26326411 | 0.80 | SLC6A4 (0.38) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL19627126 | 0.80 | SLC6A4 (0.35) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271976-A1 | OPIOID RECEPTOR MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271976-A1 | OPIOID RECEPTOR MODULATORS | OPRM1, OPRL1, OPRD1 | SLC6A4 305/4885OPRM1 1/4885OPRK1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.