SCHEMBL26326646

SCHEMBL26326646

Cc1ccc(C(C)(O)CCc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KIF11 P52732 2/20 0.41
HRH1 P35367 1/20 0.40
ATM Q13315 1/20 0.40
SLC13A5 Q86YT5 2/20 0.40
GPR52 Q9Y2T5 1/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26326648 0.89 CYP2C19 (0.47) KMT2ATDP1KIF11ALDH1A1SMN1; SMN2
SCHEMBL28598321 0.82 MEN1 (0.59) KMT2AMEN1NPC1RAB9ATDP1
SCHEMBL8683336 0.81 NPC1 (0.44) KMT2AMEN1NPC1RAB9ATDP1
SCHEMBL9589436 0.81 CYP1A2 (0.42) RAB9ALMNASMN1; SMN2
SCHEMBL19642806 0.77 GAA (0.43) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL15478310 0.77 TSHR (0.48) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL19130783 0.77 TSHR (0.48) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL31305572 0.75 TSHR (0.46) KMT2AMEN1NPC1RAB9ATDP1
SCHEMBL272368 0.74 TDP1 (0.48) KMT2AMEN1NPC1RAB9ATDP1
SCHEMBL251220 0.74 TDP1 (0.48) KMT2AMEN1NPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE HPD, TALDO1, OGG1 KMT2A 1249/4885MEN1 1296/4885NPC1 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.