Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.54 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25831270 | 0.82 | ALDH1A1 (0.55) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL23999937 | 0.81 | MAP4K4 (0.56) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL30210340 | 0.81 | MAP4K4 (0.64) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL24010989 | 0.81 | MAP4K4 (0.52) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL25491134 | 0.80 | ALDH1A1 (0.56) | MAP4K4IP6K1IP6K3MEN1KMT2A | |
| SCHEMBL23999855 | 0.79 | IP6K1 (0.55) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL30210309 | 0.79 | IP6K1 (0.63) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL23999414 | 0.79 | IP6K1 (0.51) | MAP4K4IP6K1IP6K3MEN1KMT2A | |
| SCHEMBL24003940 | 0.78 | MAP4K4 (0.56) | MAP4K4IP6K1IP6K3HRH4MEN1 | |
| SCHEMBL25820121 | 0.77 | MAP4K4 (0.49) | MAP4K4IP6K1IP6K3HRH4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAP4K4 352/4885IP6K1 202/4885IP6K3 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.