Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25440257 | 0.85 | HPGD (0.43) | HPGDPOLBCTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL26327837 | 0.80 | TP53 (0.43) | HPGDPOLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL26324989 | 0.77 | HPGD (0.42) | HPGDPOLBCTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL26325985 | 0.64 | LMNA (0.51) | HPGDSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL5720838 | 0.64 | GAA (0.47) | TAS1R3TAS1R1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL24667608 | 0.64 | NPC1 (0.48) | HPGDSMN1; SMN2KMT2AALOX15ALDH1A1 | |
| SCHEMBL26327935 | 0.63 | POLB (0.40) | POLBKMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL20564582 | 0.63 | TP53 (0.41) | HPGDPOLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL25455175 | 0.63 | KMT2A (0.60) | HPGDPOLBKMT2AALOX15ALDH1A1 | |
| SCHEMBL27290971 | 0.63 | HDAC3 (0.41) | HPGDPOLBKMT2AALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | TAS1R3 3237/4885TAS1R1 3824/4885HPGD 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.