SCHEMBL26328002

SCHEMBL26328002

CC(O)(c1cc(Cc2ccc(N)c(C(O)(C(F)(F)F)C(F)(F)F)c2)ccc1N)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 4/20 0.40
MAPT P10636 4/20 0.40
KMT2A Q03164 4/20 0.40
GAA P10253 4/20 0.40
POLB P06746 2/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 4/20 0.37
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP3A4 P08684 1/20 0.36
CDC25B P30305 1/20 0.36
CASP6 P55212 1/20 0.36
RCE1 Q9Y256 1/20 0.36
HSD17B10 Q99714 3/20 0.36
ALOX15 P16050 2/20 0.36
TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10002079 0.94 SMN1; SMN2 (0.45) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL15744799 0.93 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL26327980 0.93 SMN1; SMN2 (0.51) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL29353699 0.91 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL10036535 0.91 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL10002085 0.88 ALDH1A1 (0.42) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL13224570 0.86 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL10036534 0.84 SMN1; SMN2 (0.54) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL25587354 0.84 SMN1; SMN2 (0.54) SMN1; SMN2KDM4EMEN1MAPTKMT2A
SCHEMBL12126474 0.80 SMN1; SMN2 (0.55) SMN1; SMN2KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287178-A1 Fluorinated Diamine or Salt Thereof, Method for Producing Fluorinated Diamine or Salt Thereof, Polyamide, Method for Producing Polyamide, Polyamide Solution, Cyclized Polyamide, Method for Producing Cyclized Polyamide, Insulation for High-Frequency Electronic Component, Method for Producing Insulation for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Appliance, and Insulating Material for Producing High-Frequency Electronic Component CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-14 US disclosed